Coates set up the Bet365 Foundation in August 2012. In February 2024 it was renamed Denise Coates Foundation. It is a registered charity under English law and it donated 100 million to twenty UK charities as of 2014. In 2024 the charity donated 1 million to help families in Ukraine.

The boss of gambling firm Bet365 was paid more than 200m in just one year, which is one of the biggest salaries ever awarded in the UK. The highest paid director of Bet365 Group, believed to be founder Denise Coates, earned a salary of 213.4m in the year to March 2024.