Freshman The Winchesters, from the Supernatural trio of Robbie Thompson, Jensen Ackles and Danneel Ackles, was one of several scripted series canceled by the CW under its new ownership as the network focuses on unscripted and lower-cost scripted programming (primarily international acquisitions/co-productions) in ...

The show wasn't ever officially canceled by The CW  instead it ended at the discretion of the show's cast. It isn't the end of Supernatural as a whole, though. Ackles is in the early stages of development on a prequel series titled The Winchesters.